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What is the introduction of plant extracts?

Author: Liang

Jul. 02, 2024

Introductory Chapter: Plant Extracts

1. Introduction

Humans are dependent on plants for basic needs such as food, clothing, and shelter for centuries [1]. Plants have also been used as arrow and dart poisons for hunting, poisons for murder, hallucinogens used for ritualistic purposes, stimulants for endurance, and hunger suppression, as well as inebriants and medicines [1]. Medicinal plants have been a source of wide variety of biologically active compounds for many centuries and used extensively as crude material or as pure compounds for treating various disease conditions. Relatively 1&#;10% of plants are used by humans out of estimated 250,000&#;500,000 species of plants on Earth [2]. Plant-based traditional medicine plays a key role in the development and advancement of modern studies by serving as a starting point for the development of novelties in drug discovery [3]. Various modern drugs were extracted from traditional medicinal plants through the use of plant material following the ethno botanical leads from indigenous cures used by traditional medical systems [4]. In developing countries and rural societies, the use of medicinal plants is both a valuable resource and necessity, and furthermore, it provides a real alternative for primary healthcare systems [5].

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Plants were once the primary source of medicines in the world and since then, plants continue to provide humans with new remedies as 50% of all drugs in clinical use in the world are derived from natural products, of which higher plants contribute 25% of the total [5, 6]. The use of plants as medicines predates written human history. Knowledge of plant use was widespread in ancient civilizations. Until the middle of the nineteenth century, plants were the main therapeutic agents used by humans, and even today, their role in medicine is still relevant. It was estimated by the WHO that around 80% of the world population relied on medicinal plants as their primary healthcare source [7] and the demand is increasing in developing countries. For example, traditional medicine (TM) practices have been used for thousands of years by people in Africa, China, India and many other countries [8]. Even in developed countries, plant-based traditional medicines are often termed complementary or alternative medicine (CAM), and their use has increased steadily. For example, in the USA alone, the total estimated that herbal sales for were $4.4 billion, a significant increase from $2.5 billion in [9].

The plant chemicals used for arrow or dart poisoning purposes are largely the secondary metabolites, which are derived biosynthetically from plant primary metabolites (e.g., carbohydrates, amino acids, and lipids) and are not directly involved in the growth, development, or reproduction of plants. Secondary metabolites can be classified into several groups according to their chemical classes, such as alkaloids, terpenoids, tannins, phenolics, and others [10]. Most of these secondary metabolites are used for plants defense against predators.

Medicinal plants are now more focused than ever because they have the capability of producing many benefits to society especially for medicinal uses. The medicinal power of these plants is due to their phytochemicals which can cause definite physiological actions on the human body. Phytochemicals are natural compounds which occur in plants such as medicinal plants, vegetables, and fruits that work with nutrients and fibers to act against diseases or more specifically to protect against diseases [11, 12]. Medicinal plants because of their accessibility and affordable health care are an important source of livelihoods for indigenous and rural populations. They are also the source of many active ingredients for modern pharmaceuticals. Between 50,000 and 80,000 flowering plants are used for medicine worldwide, many of them are collected from wild resources [12]. Herb as a group of plants was also used as food (vegetables) and flavors for hundreds of years in many parts of the world. Herbs have been traditionally regarded as natural remedies for common ailments of a human. Nearly all cultures and civilizations from ancient times to the present day have used herbal medicines which are antimicrobial sources to cure infections [13]. Conventional antifungal and antibacterial treatment of infections becomes inefficient to cure patients, providing resistance of microorganisms.

1.1. Plant-derived drugs and various clinical trial stages

Table 1 shows compounds or extracts are drugs or on the process of clinical trial stage derived from plants and their therapeutic use.

Drug Plant source Disease to treat Reference Galantamine Galanthus woronowii Losinsk Alzheimer&#;s disease [14, 15] Apomorphine &#; Parkinson&#;s disease [16] Tiotropium bromide &#; Obstructive pulmonary disease [17] Varenicline &#; Smoking cessation [18, 19, 20] Betulinic acid Many plants Anticancer, antibacterial, antimalarial, anti-HIV, anthelminthic, anti-inflammatory, and antioxidant properties [21, 22] Combretastatin A4 phosphate Combretum caffrum Kuntze Anaplastic thyroid cancer [23] Huperzine A Huperzia serrata (Thunb. ex Murray) Trevis Alzheimer&#;s disease [24] Ingenol 3-angelate Euphorbia peplus L. Warts and actinic keratoses [25] Morphine Papaver somniferum Pain [26] Protopanaxadiol Panax ginseng Apoptotic effect on cancer cells [27] Harpagoside Harpagophytum procumbens DC Pain [28] Harpagophytum procumbens extract Harpagophytum procumbens Hip and knee osteoarthritis [28] Flavocoxid (Limbrel) blend of flavonoids Scutellaria baicalensis Georgi and Acacia catechu Willd Osteoarthritis [1] Ginkgo extract Ginkgo biloba L. Alzheimer&#;s disease [29] Mistletoe extract (Iscador) Viscum album L. Various cancer [30] Sativex extract Cannabis sativa L. Neuropathic pain [31]

Table 1.

Compounds and extracts derived from plants used as drugs or on the process of clinical trial stage.

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A brief introduction to plant extracts

Plant extracts are based on plants as raw materials. According to the needs of the use of the final product extracted, through physical and chemical extraction and separation processes, one or more effective ingredients in the plant are obtained and concentrated without changing the effective ingredients. The product formed by the structure. At present, the product concept of plant extracts is relatively broad. According to the different components of the extracted plants, glycosides, acids, polyphenols, polysaccharides, terpenoids, flavonoids, alkaloids, etc. are formed; according to the properties of the final product, it can be divided into vegetable oil, extract, powder, lens, etc.

In recent years, the plant extract industry has developed rapidly and is widely used in food, medicine, and chemical industries. It is an important export variety of Chinese medicine products and occupies half of it.

KH Health Industry Co., Ltd., that a subsidiary of Riotto botanical Co.,Ltd which is located in Xi'an .It is a high-tech export-oriented manufacturing enterprise dedicated to the development of plant extracts, organic fruit and vegetable powder, customized formulas for customers and implementation of production. The company's subsidiary Beton Nutrition Corporation. specializes in international trade, dedicated to the trade of amino acids, vitamins, APIs and other products.

Our company&#;s main products are olive leaf extract, black garlic extract, ginger extract, ginseng extract, turmeric extract, aloe extract, elderberry extract, milk thistle extract etc,are all popular herbal supplements Agent.

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For more plant extract manufacturerinformation, please contact us. We will provide professional answers.

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